Today we released version 4.0 of the Analyse-it Method Validation edition. This is a major new release with many new features and improvements.
The latest release of the Analyse-it Method Validation edition now supports 10 of the latest CLSI evaluation protocol (EP) guidelines. CLSI guidelines are world-renowned and are recognized by the College of American Pathologists (CAP), The Joint Commission, and the US Food and Drug Administration (FDA).
Analyse-it has been a driving force in the adoption of statistics in method validation for over 15 years, has influenced many recommendations, and is the only software available with such extensive coverage for the latest CLSI guideles.
CLSI guidelines supported in version 4.0 include:
Measurement Systems Analysis (MSA) is a new feature in version 4.0. MSA unifies precision and linearity, which were available in earlier versions of Analyse-it, but also includes trueness (bias) and detection capability so you can establish the limit of blank (LoB) and limit of detection (LoD). The unification of these analyses in MSA lets you dig deep to examine and understand the performance characteristics of a measurement procedure.
A major improvement in version 4.0 is the ability to split a method comparison analysis into specific measuring intervals and apply a different analysis. For example, you might split the analysis into two measuring intervals: samples <1ug/L, and those above. For <1ug/L the relationship between measurements might be different from those >1 ug/L, so you can apply different fits and goals to each measuring interval to see how the methods compare.
Similarly, for reference intervals you can apply partitioning factors to generate reference intervals for different sub-groups. For example, you might apply partitioning factors sex and age group so you can determine reference intervals for age groups 0-20, 20-35, 35-50, and 50+ for male / female subjects. For each subgroup you can change how the reference interval is calculated, for example using the robust reference interval calculation for a sub-group with very few subjects.
If you already have a licence for Analyse-it, and you have active maintenance (access to software updates), you can download the latest version now. If maintenance on your licence has lapsed, now is a good time to renew maintenance to get this update and future updates before the price increase (see below).
To download the update, check whether you have maintenance, or to renew maintenance, see:
The cost of a 1-user perpetual licence for the Analyse-it Method Validation will increase from US$699 to US$749, and the cost of a 1 floating-user perpetual licence will crease from US$1239 to US$1329 from the 7th July 2015. Since maintenance is based on a percentage of the licence price, the 1-year maintenance renewal price for a 1-user perpetual licence will increase slightly from US$69.90 to US$74.90.
We will also be trialling a new option to purchase a 1-year annual subscription for the Analyse-it Method Validation edition from the 7th July 2015. The cost will be US$ 449 for 1-year and includes all software updates released within the year. At the end of the year you can renew your licence to continue using the software, or let the licence lapse if you no longer need it.
Finally, below is a list of the major changes and improvements in version 4.0.
Detection capability NEW
The recent of passing of Professor Rick Jones (see ) caused me to reflect on the past.
I was very fortunate to earn a work placement with Dr Rick Jones at The University of Leeds in the summer of 1990. Rick was enthusiastic about the role of IT in medicine, and after securing funding for a full-time position he employed me as a computer programmer. Early projects included software for automating the monitoring of various blood marker tests and software to diagnose Down’s syndrome. At the time many hospitals had in-house solutions for diagnosing Down’s syndrome, and although the project took many years and the help of many other people to complete, it eventually gained widespread adoption.
Today we released version 3.80 of the Analyse-it Standard edition.
The new release includes Principal Component Analysis (PCA), an extension to the multivariate analysis already available in Analyse-it. It also includes probably the most advanced implementation of biplots available in any commercial package.
New features include:
The tutorial walks you through a guided example looking at how to use correlation and principal component analysis to discover the underlying relationships in data about New York Neighbourhoods. It demonstrates the amazing new features and helps you understand how to use them. You can either follow the tutorial yourself, at your own pace, or .
If you you will no doubt already know about the recent improvements in the Analyse-it Method Validation edition and the release of our first video tutorial. If not, now is a good time to since we post short announcements and feature previews on Facebook, and use the blog only for news about major releases.
The latest changes and improvements to the Analyse-it Method Validation edition include:
Today we released version 3.70 of Analyse-it.
The new version includes many new features which some of you may have read about on our page over the last few weeks:
New features include:
If you have you will be notified an update is available when you next start Analyse-it, or you can download and install the update now, see . If maintenance on your licence has expired now is a good time to renew it to get this update and forthcoming updates, see .
Probably the greatest concern when using statistical software is reliability. Is the software producing accurate, numerically correct results that have been validated?
It’s a very important question. Many of you work in FDA and regulated environments where the penalties for mistakes are very high. And those of you outside such environments are still making important business and research decisions using Analyse-it. It’s therefore imperative that the software you depend upon is developed to a professional standard, thoroughly tested and validated.
We have just released version 3.60 of the Analyse-it Standard edition. It now includes repeat-measures ANOVA and Friedman tests in the Compare Pairs analysis.
If you have active maintenance, Analyse-it will notify you an update is available in the next few days, or you can download it immediately at:
If you do not have active maintenance, now is a great time to extend maintenance to get this latest update and all updates for the next 1- or 3-years, see:
Today we released the Analyse-it Method Validation edition version 3.5. The software is feature complete, validated, and includes documentation. It supports Excel 2007, Excel 2010 (32- and 64-bit) and Excel 2013 (32- and 64-bit).
We took this opportunity to rename the product from the Analyse-it Method Evaluation edition to the Method Validation edition. The product is the same, but the new name better reflects the intended purpose of the product.
Today we released the first public beta test version of the Analyse-it Method Evaluation edition, version 3.5. The software is feature complete and is validated – it is now only missing documentation.
We invite everyone to download the beta and try the new version of the software before it is finally released in September. You will need Excel 2007, 2010, or 2013 (32-bit and 64-bit versions are supported) and it can be installed and used alongside older versions of Analyse-it so it won't interrupt your day-to-day work.
Today we released the 3rd alpha release of the Analyse-it Method Evaluation Edition 3.5. Alpha releases are versions of the software that are still in active development, but are released to small group of customers so we can identify and fix any problems before the public beta release.
This release now completes the package with method comparison, which includes Deming regression, Passing-Bablok regression, and Bland-Altman difference plots. Linearity, precision analysis, diagnostic performance (ROC analysis and binary test performance) and reference intervals were already included in earlier alpha releases.
Analyse-it is the leading statistics software for Microsoft Excel.
First released in 1997, Analyse-it surpasses traditional statistical software in ease of use, features and price. Over 25,000 customers now rely on Analyse-it for in-depth statistical analysis and visualization in Excel.