The recent of passing of Professor Rick Jones (see Rick Jones obituary) caused me to reflect on the past.
I was very fortunate to earn a work placement with Dr Rick Jones at The University of Leeds in the summer of 1990. Rick was enthusiastic about the role of IT in medicine, and after securing funding for a full-time position he employed me as a computer programmer. Early projects included software for automating the monitoring of various blood marker tests and software to diagnose Down’s syndrome. At the time many hospitals had in-house solutions for diagnosing Down’s syndrome, and although the project took many years and the help of many other people to complete, it eventually gained widespread adoption.
Around 1992, Rick came up with the idea of a statistics package that integrated into Microsoft Excel. Armed with a ring bound folder containing the Excel SDK and a pile of medical statistics books, I set about the task of writing the software in C++. It wasn’t long before the first version of Astute was ready and commercially released.
Never short of ideas for new projects, Rick started leaving journal articles in my in-tray covering subjects such as Deming and Passing-Bablok regression, Galen-Gambino sensitivity/specificity and ROC analysis. Rick had widespread experience and knowledge of the statistics needed in the clinical laboratory, and was keen to make the subject less daunting and more accessible to clinicians. The plan was to extend Astute to include these new statistical techniques. It would be an entirely new type of statistics package, so new in fact that when we released the product we didn’t have a good name for it and it was simply called “Astute - Module 1”.
Rick later co-authored the book Clinical Investigation and Statistics in Laboratory Medicine and it helped many clinicians better understand and appreciate the use of statistics in the laboratory.
Eventually, I moved on from Leeds University to co-found Analyse-it, and develop the successor to Astute. The ‘Module 1’ product transformed into the Clinical Laboratory Module and later into the Method Validation Edition. From its conception in Astute, to its implementation to Analyse-it, the product has transformed method validation in clinical laboratories and in-vitro diagnostic companies around the world.
Without Rick, Analyse-it would not exist today. Rick was the original catalyst and visionary for the product. Although I am writing this with great sadness, reflecting on the past, Rick’s enthusiasm for life leaves me positive and inspired. His inspiration will live on through Analyse-it.
Today we released version 3.80 of the Analyse-it Standard edition.
The new release includes Principal Component Analysis (PCA), an extension to the multivariate analysis already available in Analyse-it. It also includes probably the most advanced implementation of biplots available in any commercial package.
New features include:
The tutorial walks you through a guided example looking at how to use correlation and principal component analysis to discover the underlying relationships in data about New York Neighbourhoods. It demonstrates the amazing new features and helps you understand how to use them. You can either follow the tutorial yourself, at your own pace, or .
If you you will no doubt already know about the recent improvements in the Analyse-it Method Validation edition and the release of our first video tutorial. If not, now is a good time to since we post short announcements and feature previews on Facebook, and use the blog only for news about major releases.
The latest changes and improvements to the Analyse-it Method Validation edition include:
Today we released version 3.70 of Analyse-it.
The new version includes many new features which some of you may have read about on our page over the last few weeks:
New features include:
If you have you will be notified an update is available when you next start Analyse-it, or you can download and install the update now, see . If maintenance on your licence has expired now is a good time to renew it to get this update and forthcoming updates, see .
Probably the greatest concern when using statistical software is reliability. Is the software producing accurate, numerically correct results that have been validated?
It’s a very important question. Many of you work in FDA and regulated environments where the penalties for mistakes are very high. And those of you outside such environments are still making important business and research decisions using Analyse-it. It’s therefore imperative that the software you depend upon is developed to a professional standard, thoroughly tested and validated.
We have just released version 3.60 of the Analyse-it Standard edition. It now includes repeat-measures ANOVA and Friedman tests in the Compare Pairs analysis.
If you have active maintenance, Analyse-it will notify you an update is available in the next few days, or you can download it immediately at:
If you do not have active maintenance, now is a great time to extend maintenance to get this latest update and all updates for the next 1- or 3-years, see:
Today we released the Analyse-it Method Validation edition version 3.5. The software is feature complete, validated, and includes documentation. It supports Excel 2007, Excel 2010 (32- and 64-bit) and Excel 2013 (32- and 64-bit).
We took this opportunity to rename the product from the Analyse-it Method Evaluation edition to the Method Validation edition. The product is the same, but the new name better reflects the intended purpose of the product.
Today we released the first public beta test version of the Analyse-it Method Evaluation edition, version 3.5. The software is feature complete and is validated – it is now only missing documentation.
We invite everyone to download the beta and try the new version of the software before it is finally released in September. You will need Excel 2007, 2010, or 2013 (32-bit and 64-bit versions are supported) and it can be installed and used alongside older versions of Analyse-it so it won't interrupt your day-to-day work.
Today we released the 3rd alpha release of the Analyse-it Method Evaluation Edition 3.5. Alpha releases are versions of the software that are still in active development, but are released to small group of customers so we can identify and fix any problems before the public beta release.
This release now completes the package with method comparison, which includes Deming regression, Passing-Bablok regression, and Bland-Altman difference plots. Linearity, precision analysis, diagnostic performance (ROC analysis and binary test performance) and reference intervals were already included in earlier alpha releases.
Today we released the 2nd alpha of the Analyse-it Method Evaluation Edition 3.5.
Alpha releases are pre-release versions of the software that are still in active development. We release them to a small group of customers so we can get feedback and quickly identify and fix any problems before the public beta release. If you want to take part in the test phase reply or comment on to this post or . You can use pre-release versions of Analyse-it alongside your
existing version of Analyse-it, so it won't disrupt your work. And, if you help during in the test phases you will get a discount on the upgrade (a free upgrade for those who contribute the most) when the product is released later this year.
Analyse-it is the leading statistics software for Microsoft Excel.
First released in 1997, Analyse-it surpasses traditional statistical software in ease of use, features and price. Over 25,000 customers now rely on Analyse-it for in-depth statistical analysis and visualization in Excel.