Deming regression software Analyse‑it provides a validated implementation of Deming & Weighted-Deming regression so you can assess agreement, quantify bias, and meet CLSI EP09‑A3 requirements — all within Excel.

Trusted by over 60,000 users at top-10 IVD manufacturers for more than 30 years.

Accurate, compliant Deming regression
Apply Deming or Weighted Deming regression to compare methods when both have measurement error. Analyse‑it follows CLSI EP09‑A3 guidance to ensure your results meet regulatory and clinical expectations.
Confirm method comparability
Detect proportional or constant bias quickly and decide with confidence whether a new or updated method matches your reference method.
Detect proportional bias and non‑constant precision
Identify proportional bias and determine whether precision is constant or varies across the measuring range.
Bias at decision points
Test bias at clinically critical thresholds to confirm you can meet claimed performance and support verification or validation studies.
Support for replicate measurements
Handle singlicate, duplicate, and replicate measurements, correctly estimating within‑subject variation and adjusting limits of agreement accordingly.
Partition into measuring intervals
Split data into intervals when precision varies and apply the appropriate analysis to each segment.
Runs in Microsoft Excel for easy deployment across your team.
Analyse‑it integrates directly into Excel. It performs all calculations and is validated to ensure accuracy -- no formulas, or cell references break. Import data from instruments, analyse it immediately, then generate publication‑ready reports without learning new software or managing proprietary file formats — significantly faster and more flexible than standalone tools.

We use Analyse-it frequently for our verification and pre-verification work, in accordance with CLSI guidelines for in-vitro diagnostics. It's saved time and effort compared to the hodge-podge of applications we used before, JMP, SAS, etc...

Brian Noland, Ph.D.

Principle Scientist, Product Development

Biosite / Inverness Medical Innovations
We use Analyse-it for the analysis of data necessary to file 510k. We chose Analyse-it because it works in Excel, includes CLSI protocols, and, unlike EP-Evaluator, lets us analyze data directly from equipment without typing.

Thomas D Harrigan, Ph.D.

Technical Product Manager

Alfa Wassermann Diagnostic Technologies
I used Analyse-It for many product development, product troubleshooting, and technology evaluation activities... your product was the easiest to use, was accurate, and produced publication ready reports.

Stanley F. Cernosek, Ph.D.

Clinical Chemistry Reagent Development

Beckman Coulter, Inc.
Analyse-it has been a tremendous help. I've published and presented at national cardiology meetings and couldn't have accomplished most of my research without it. Using Analyse-it, I even found errors or omissions in the work of our statistician!

Regina S. Druz, MD, FACC, FASNC

Director, Nuclear Cardiology

North Shore University Hospital
Although we only scratch the surface of Analyse-it’s capabilities, we have a very high volume of use for the statistics we need. It’s saved us time and the reports look professional.

Michael Savage

Chemistry Supervisor

Baptist Hospital East

* Available in the Method Validation and Ultimate editions.

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