Analyse-it Method Validation edition, version 4.00
- Support for CLSI guidelines
Reference interval
- Partition factors for separate reference interval analysis of sub-groups.
- Additional transformation functions: Manly exponential, 2-stage Exponential/Modulus transformation.
- Normal MVUE quantile estimator for reference limits.
Diagnostic performance
- Bi-Histogram and dot-pot of the distribution of positive/negative cases.
Method comparison
- Adjust measuring interval to a linear range and extrapolate fits beyond the data to the measuring interval.
- Partition into measuring intervals, with different relationships (e.g. constant / relative differences or variances) for each measuring interval.
Linearity
- Improved report and plots.
- Integrated into MSA to allow unified approach to evaluation of other components of error.
Precision
- Improved report and plots.
- Precision profile variance function fits with a choice of 7 fits, including Sadler 3-parameter functions.
- Limit of quantitation via prediction from CV% on precision profile plot.
Trueness (NEW!)
- Estimate bias with reference materials or PT/EQA material.
Detection capability (NEW!)
- Estimate the decision level critical value (LoB) using parametric and non-parametric estimator on blank material or via the precision profile variance function.
- Estimate the detection limit (LoD) using non-blank material or via the precision profile variance function.
