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Bland-Altman method comparison tutorial

Learn how to assess the agreement between two methods of measurement.

In a 1986 issue of The Lancet, Bland & Altman published a paper that changed how method comparison studies are performed. In 1999, they published a follow-up paper that extended their earlier work to many different scenarios.

If you prefer you can watch a video of this tutorial.

In this tutorial you will perform the following tasks:

  1. Plotting the relationship between methods
  2. Estimating the average bias and the limits of agreement
  3. Understanding the importance of repeatability
  4. Using repeated measurements
  5. Dealing with a relationship between difference and magnitude of measurement
  6. Transforming the measurements to remove a relationship between differences and magnitude
  7. Estimating regression based limits of agreement when transformation is not enough
  8. Estimating nonparametric limits of agreement in non-normally distributed data
Related information
Altman, D. G., & Bland, J. M. (1983). Measurement in medicine: the analysis of method comparison studies. The statistician, 307-317.
Martin Bland, J., & Altman, D. (1986). Statistical methods for assessing agreement between two methods of clinical measurement. The lancet, 327(8476), 307-310.
Bland, J. M., & Altman, D. G. (1999). Measuring agreement in method comparison studies. Statistical methods in medical research, 8(2), 135-160.

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  •  Association in 2-way contingency tables tutorial
  •  Simple linear regression tutorial
  •  Bland-Altman method comparison tutorial
  •  Plotting the relationship between methods
  •  Estimating the average bias and the limits of agreement
  •  Understanding the importance of repeatability
  •  Using repeated measurements
  •  Dealing with a relationship between difference and magnitude of measurement
  •  Transforming the measurements to remove a relationship between differences and magnitude
  •  Estimating regression based limits of agreement when transformation is not enough
  •  Estimating nonparametric limits of agreement in non-normally distributed data
  •  Estimating the precision of a measurement procedure (CLSI EP05-A3)
  •  Evaluating the linearity of a measurement procedure (CLSI EP06-A)
  •  Verifying the precision of a measurement procedure against a performance claim and estimating the bias (CLSI EP15-A3)
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Version 6.15
Published 18-Apr-2023
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