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  • Evaluating the linearity of a measurement procedure (CLSI EP06-A)

Reducing the measuring interval

Reduce the measuring interval to find the interval where the fit is linear.

Sometimes it is possible to reduce the measuring interval to a smaller range that is still useful.

  1. On the Analyse-it ribbon tab, in the Statistical Analyses group, click Adjust Interval.

    The measuring interval drop-down lists show.

  2. In the Measuring interval drop-down lists, select ≥ 1 and ≤ 5.
  3. Click Recalculate.

    The analysis report updates.

The linearity plot differences now lie within the allowable nonlinearity of 0.2 mg/dL. Therefore, the method is declared as linear within 0.2mg/dL between the reduced interval 4.65 and 15.4 mg/dL.


EP06 linearity plot showing linearity

  •  Tutorials
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  •  Simple linear regression tutorial
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  •  Estimating the precision of a measurement procedure (CLSI EP05-A3)
  •  Evaluating the linearity of a measurement procedure (CLSI EP06-A)
  •  Estimating linearity
  •  Reducing the measuring interval
  •  Verifying the precision of a measurement procedure against a performance claim and estimating the bias (CLSI EP15-A3)
  •  Pareto charts tutorial
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Published 18-Apr-2023
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Statistical analysis and method validation software for Microsoft Excel.

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