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  • Estimating the precision of a measurement procedure (CLSI EP05-A3)

Fitting a precision profile

Fit a precision profile function to describe the imprecision across the measuring interval.

  1. On the Analyse-it ribbon tab, in the MSA group, click Profile.
    The Precision Profile panel opens in the analysis task pane.
  2. In the Precision profile drop-down list, select CV%.
  3. Select the Reproducibility, Within Factor A, and Repeatability check boxes.
  4. Select the Logarithmic X-axis scale check box so that the scale of the precision profile will show the lower levels more clearly.
  5. Select the Fit variance function check-box and then in the Model drop-down, select 3-parameter.
  6. Click Recalculate.

    The analysis report updates.

The precision profile show the relationship between the imprecision and the measurand level. The variance function fit describes the relationship as a continuous function.

The variance function describes the relationship between the variance and concentration using a 3-parameter power model typically used for immunoassays.

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  •  Estimating the precision of a measurement procedure (CLSI EP05-A3)
  •  Estimating precision
  •  Estimating precision for a multi-site study
  •  Fitting a precision profile
  •  Evaluating the linearity of a measurement procedure (CLSI EP06-A)
  •  Verifying the precision of a measurement procedure against a performance claim and estimating the bias (CLSI EP15-A3)
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Version 6.15
Published 18-Apr-2023
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Statistical analysis and method validation software for Microsoft Excel.

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