We are receiving a lot of questions about relevant analyses in the Analyse-it Method Validation edition to help in evaluating new diagnostic tests in the fight against COVID-19. Below are some quick links that will help, but contact us if you have questions - we are working as normal.
Also see our latest blog post: Sensitivity/Specificity and The Importance of Predictive Values for a COVID-19 test
Capability ratios (Cp/Pp) describe the variability of a process relative to the
A capability ratio is a unit-less value describing the ratio of process distribution spread to specification limits spread. A value of less than 1 is unacceptable, with values greater than 1.33 (1.25 for one-sided specification limits) widely accepted as the minimum acceptable value, and values greater than 1.50 (1.45 for one-sided specification limits) for critical parameters (Montgomery, 2012). The higher the value, the more capable the process of meeting specifications. A
value of 2 or higher is required to achieve Six Sigma capability which is defined as the process mean not closer than six standard deviations from the nearest specification limit.
All of the indices assume a normally distributed process quality characteristic with the parameters specified by the process mean and sigma. The process sigma is either the short-term or long-term sigma estimate.
Indices computed using the short-term sigma estimate are called Cp indices (Cp, Cpl, Cpu, Cpk, Cpm). While those using long-term sigma estimate are called Pp indices (Pp, Ppl, Ppu, Ppk, Ppm). If the Cp indices are much smaller than the Pp indices, it indicates that there are improvements you could make by eliminating shifts and drifts in the process mean.