We are receiving a lot of questions about relevant analyses in the Analyse-it Method Validation edition to help in evaluating new diagnostic tests in the fight against COVID-19. Below are some quick links that will help, but contact us if you have questions - we are working as normal.
Also see our latest blog post: Sensitivity/Specificity and The Importance of Predictive Values for a COVID-19 test
Nonlinear bias is a component of bias that cannot be represented by a linear relationship between the measured and true values.
A measurement procedure is linear when there is a mathematically verified straight-line
relationship between the measured and true values. It is an important parameter as it allows
linear interpolation of results between points.
Bias due to nonlinearity is measured as the difference between the linear fit and the best fitting polynomial fit.