We are receiving a lot of questions about relevant analyses in the Analyse-it Method Validation edition to help in evaluating new diagnostic tests in the fight against COVID-19. Below are some quick links that will help, but contact us if you have questions - we are working as normal.

- CLSI EP12-A2 for diagnostic accuracy see Sensitivity/Specificity, Predictive values, Estimating the sensitivity and specificity of a binary test and Comparing the accuracy of two binary diagnostic test.
- CLSI EP17-A2 for detection capability of molecular methods using Probit analysis, see: Estimating the detection limit using a Probit fit and may be useful for determining the cutoff of a method with an internal continuous response see: Estimating the detection limit of a measurement system and Estimating the detection limit of a measurement system using a precision profile.

Also see our latest blog post: Sensitivity/Specificity and The Importance of Predictive Values for a COVID-19 test

EP12-A2 Example: Sensitivity specificity of 2 diagnostic tests EP17-A2 Example 1:LoB and LoD EP17-A2 Example 2:

LoD from precision profile EP17-A2 Example 4:

Probit detection limit