Blog: Method validation Release notes, how-tos and statistical explainers from the Analyse-it team, newest first.
- 2021
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Analyse-it 5.90: Support for the updated CLSI EP6-Ed2 protocol and inverse predictions
Recently we’ve been busy updating Analyse-it to stay aligned with the latest updates to the CLSI protocols, and added a new inverse prediction feature.
- 2020
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Calculating the detection limit for a SARS-CoV-2 RT-PCR assay using Analyse-it
Recent improvements to the Analyse-it Method Validation edition, in version 5.50 and later, include the addition of probit regression. Probit regression is useful when establishing the detection limit (LoD) for an RT-qPCR assay.
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Calculating PPA/NPA agreement measures using Analyse-it
Following our last blog post, today, we will show how to calculate binary agreement using the Analyse-it Method Validation edition. The CLSI EP12: User Protocol for Evaluation of Qualitative Test Performance protocol is a useful companion resource for laboratories and diagnostic…
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Diagnostic accuracy (sensitivity/specificity) versus agreement (PPA/NPA) statistics
Due to COVID-19, there is currently a lot of interest surrounding the sensitivity and specificity of a diagnostic test. These terms relate to the accuracy of a test in diagnosing an illness or condition.
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Establishing the diagnostic accuracy (sensitivity/specificity) of a test using Analyse-it
It is important in diagnostic accuracy studies that the true clinical state of the patient is known. For example, in developing a SARS-CoV-2 anti-body test, for the positive subgroup, you might enlist subjects who had a positive SARS-CoV-2 PCR test and clinically confirmed…
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Why the diagnostic test 'accuracy' statistic is useless
In our last post, we mentioned that the 'accuracy' statistic, also known as the probability of a correct result, was a useless measure for diagnostic test performance. Today we'll explain why.
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Sensitivity/Specificity and The Importance of Predictive Values for a diagnostic test
There’s currently a lot of press attention surrounding the finger-prick antibody IgG/IgM strip test to detect if a person has had COVID-19. Here in the UK companies are buying them to test their staff, and some in the media are asking why the government hasn’t made millions of…
- 2017
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Analyse-it 4.90 released: Prediction intervals, EP14-A3 and EP30-A
Prediction intervals on Deming regression are a major new feature in the Analyse-it Method Validation Edition version 4.90, just released.
- 2016
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Analyse-it 4.60 released: 3 nested factor precision
Today we released version 4.60 of the Analyse-it Method Validation edition. The new release now includes 3 nested-factor precision analysis, which extends Analyse-it’s support for CLSI EP05-A3 multi-laboratory precision studies.
- 2015
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Analyse-it 4.0 released: Support for CLSI guidelines, and Measurement Systems Analysis
Today we released version 4.0 of the Analyse-it Method Validation edition. This is a major new release with many new features and improvements.
- 2014
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A sombre note: Professor Rick Jones
The recent of passing of Professor Rick Jones (see Rick Jones obituary) caused me to reflect on the past.
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Recent improvements in Analyse-it 3.76 and our first video tutorial!
If you follow us on Facebook you will no doubt already know about the recent improvements in the Analyse-it Method Validation edition and the release of our first video tutorial.
- 2013
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Analyse-it Method Validation edition version 3.5 is now available
Today we released the Analyse-it Method Validation edition version 3.5. The software is feature complete, validated, and includes documentation. It supports Excel 2007, Excel 2010 (32- and 64-bit) and Excel 2013 (32- and 64-bit).
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Join the Analyse-it Method Evaluation 3.5 public beta test and earn a free upgrade!
The Analyse-it Method Validation Edition version 3.50 has now been released, see Analyse-it Method Validation edition version 3.5 is now available.
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Analyse-it Method Evaluation Edition 3.5 alpha 3 now available
The Analyse-it Method Validation Edition version 3.50 has now been released, see Analyse-it Method Validation edition version 3.5 is now available.
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Analyse-it Method Evaluation Edition 3.5 alpha 2 now available
The Analyse-it Method Validation Edition version 3.50 has now been released, see Analyse-it Method Validation edition version 3.5 is now available.
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Announcing the Analyse-it Method Evaluation Edition 3.5
The Analyse-it Method Validation Edition version 3.50 has now been released, see Analyse-it Method Validation edition version 3.5 is now available.
- 2008
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Analyse-it speeds Method Validation at National Laboratory
Today we’re delighted to publish the second case study into the use of Analyse-it. The case study features a national clinical laboratory in the USA that offers more than 2,000 tests and combinations to major commercial and government laboratories.
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Analyse-it Cuts Project Time in Half at Swiss Lab
Today we’re delighted to publish the first case study into the use of Analyse-it. Marco Balerna Ph.D., a Clinical Chemist at the EOC (Ente Ospedaliero Cantonale) in Switzerland, used Analyse-it when replacing the clinical chemistry and immunological analysers in EOC’s…