We are receiving a lot of questions about relevant analyses in the Analyse-it Method Validation edition to help in evaluating new diagnostic tests in the fight against COVID-19. Below are some quick links that will help, but contact us if you have questions - we are working as normal.

CLSI EP12-A2 for diagnostic accuracy see Sensitivity/Specificity, Predictive values, Estimating the sensitivity and specificity of a binary test and Comparing the accuracy of two binary diagnostic test.
CLSI EP17-A2 for detection capability of molecular methods using Probit analysis, see: Estimating the detection limit using a Probit fit and may be useful for determining the cutoff of a method with an internal continuous response see: Estimating the detection limit of a measurement system and Estimating the detection limit of a measurement system using a precision profile.

Also see our latest blog post: Sensitivity/Specificity and The Importance of Predictive Values for a COVID-19 test

EP12-A2 Example: Sensitivity specificity of 2 diagnostic tests

EP17-A2 Example 1:
LoB and LoD

EP17-A2 Example 2:
LoD from precision profile

EP17-A2 Example 4:
Probit detection limit

Fitting a simple logistic regression

Fit a simple logistic regression model to describe the relationship between a single predictor variable and a binary response variable.

Select a cell in the dataset.
On the Analyse-it ribbon tab, in the Statistical Analyses group, click Fit Model, and then click Logit / Logistic.
The analysis task pane opens.
In the Y drop-down list, select the binary response variable.
In the Event drop-down list, select the outcome of interest.
In the X drop-down list, select the predictor variable.
Optional: To show log odds ratio, select the Parameter estimates check box.
Optional: To show odds ratio, select the Odds ratio estimates check box.
Click Calculate.

Related concepts

Parameter estimates

Odds ratio estimates

Effect of model hypothesis test

Effect of term hypothesis test

Related tasks

Fitting an advanced logistic model

Related reference

Dataset layout

Available in Analyse-it Editions
Standard edition
Method Validation edition
Quality Control & Improvement edition
Ultimate edition